Since pharmaceutical sciences consist of a broad range of academic disciplines, a wide variety of instruments are absolutely imperative to achieve meaty education and research. However, all of the instruments possess own durable life and period of guarantee and the time-varying deterioration is an unavoidable problem. Therefore, the maintenance, management and update of instruments at an appropriate interval are crucially important. The Research Instruments Center is in charge of the management of chiefly large-size research instruments by the cooperation of highly professional faculty members and facility staffs in our university. Because there is a definite ceiling to maintain over-budgeted instruments for a single-department school in pharmaceutical sciences, the Research Instruments Center carves the number of instruments down to the minimum necessary. In the last 10 years, a cooperative framework between Gifu University and Gifu Pharmaceutical University is vigorously building to reduce overlap in research instruments via the mutual exploitation of both instruments. While it can take a certain level of adjustment to establish an attractive way because each university has different faculties, the Research Instruments Center plans to create a mutually beneficial system.